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In a Danish nationwide study, just over half of adults without diabetes who started semaglutide for weight loss discontinued within a year. Discontinuation was highest among younger adults (18–30 years), men, those
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Most quit breakthrough weight-loss drug within a year
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Association between socioeconomic factors and semaglutide use for weight loss: a population-based cross-sectional study in Denmark
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00225-6/asset/68cceef6-7233-4e0d-b0f0-edf8de7915d5/main.assets/gr2_lrg.jpg "Once-weekly semaglutide 7·2 mg in adults with obesity and type 2 diabetes (STEP UP T2D): a randomised, controlled, phase 3b trial")
Once-weekly semaglutide 7·2 mg in adults with obesity and type 2 diabetes (STEP UP T2D): a randomised, controlled, phase 3b trial
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New real-world data show that over half of people who stop GLP-1 weight-loss drugs regain some weight within a year. The findings align with clinical trial data: once treatment stops, weight typically
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ISPOR 2025: Exploring reasons for GLP-1 discontinuation
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Two Years After Stopping GLP-1s, Most Patients Sustain at Least Some Weight Loss
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