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SCALE (NEJM 2015) was the pivotal trial for liraglutide 3.0 mg — the first GLP-1 RA approved for chronic weight management. In 3,731 adults with obesity, it produced 8.0% mean weight loss
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Many patients maintain weight loss a year after stopping semaglutide, liraglutide
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Semaglutide VS Liraglutide -- 根據美國糖尿病學會的這篇論文 2017年上市的Semaglutide 不論是 HbA1c的下降幅度， 還是 晨間空腹血糖、 或是 體重下降的幅度， 甚至 腰圍縮小的程度 效果都比Liraglutide來的好 -- Reference A 26-Week Randomized Controlled Trial of
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Liraglutide vs Semaglutide: Which Works Best for You?
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Efficacy of the Glucagon-Like Peptide-1 Receptor Agonists Liraglutide and Semaglutide for the Treatment of Weight Regain After Bariatric surgery: a Retrospective Observational Study | Obesity Surgery
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