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select trial semaglutide nejm LEADER (NEJM 2016) was the landmark CVOT for liraglutide in T2DM. In 9,340 patients at high cardiovascular risk, liraglutide reduced 3-point MACE by 13% (HR 0.87; p=0.01) and cardiovascular death by 22% (

Marsoni M251S
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Verified Purchase
Careful shopper
Los Angeles, US
★★★★★ 4
Whitens but not a pleasant taste.
Yes, it whitens teeth but is abrasive. Not sure how good it is for enamel, and it tastes terrible.
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Reviewed in the United States on February 18, 2026
L
Verified Purchase
Lugo's Home
Port Orchard, US
★★★★★ 5
Great Toothpaste Alternative
I really like this teeth whitening powder. It is easy to use and leaves my mouth feeling clean and fresh. I also appreciate that it is made with nano hydroxyapatite and is designed for sensitive teeth. It has become a great addition to my oral care routine, and I am very happy with this product.
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Reviewed in the United States on May 29, 2026
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Verified Purchase
Laura
Lake Worth, US
★★★★★ 5
Effective!
Noticeable difference after 2 uses! No harsh taste either!
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Reviewed in the United States on May 30, 2026
P
Verified Purchase
pri
Lexington, US
★★★★★ 3
it's not bad
a coffee, tea, and alcohol drinker so i've gone thru a few of these. i knew i wouldn't see immediate results so i just tried to consistently brush my teeth with this. i can't say it made my teeth whiter but i think it brightened my teeth and helps to prevent it from staining? i didn't irritate my teeth or gums which is important, it helped my mouth to feel cleaner or was it bc of the flavors in it that makes it feel like that? also this little container is too expensive!
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Reviewed in the United States on February 14, 2026
A
Verified Purchase
Amazon Customer
Grantham, US
★★★★★ 5
Great Product
Its a good product. It works gradually whitening teeth. I use this powder on top of the Boka Prebiotic toothpaste and I have to say I am pretty impressed how clean my teeth are, the whitening and no sensitivity issues.
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Reviewed in the United States on May 30, 2026

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